Drugs to be Discontinued: Cyanide Antidote Kit
Wednesday, 30 May 2012 11:25
updated
10/10/2007
888-825-5249
Letter from GlaxoSmithKline (updated 10/10/2007)
Alcohol in 5% Dextrose Injection, USP, Glass Container
12/19/2007
Hospira, Inc.877-946-7747Hospira has made a business decision to discontinue manufacturing of 5% Alcohol in 5% Dextrose Injection drug product (NDC# 0409-1500-05)
Aminophylline Tablets USP, 100 mg and 200 mg
4/4/2012
West-Ward Pharmaceutical Corp.
1-800-631-2174
Brevibloc Concentrate (esmolol HCl) 250 mg/mL, 10 mL ampul
8/24/2007
Baxter Healthcare CorporationBaxter Healthcare Corporation has made a decision to discontinue Brevibloc Concentrate (esmolol HCl) 250 mg/mL, 10 mL ampul (NDC 10019-025-18 for the pack and NDC 10019-025-73 for the ampul). Letter from BaxterCalciferol injection in oil (ergocalciferol)
3/19/2004
Schwarz Pharma6140 W. Executive Drive
Mequon, WI 53092
800-558-5114
Schwarz has discontinued manufacturing of calciferol
Calcitriol 1 mcg/mL Injection5/18/2012West-Ward Pharmaceuticals
Customer Service:
1-888-229-0001West-Ward no longer distributes Calcitriol 1 mcg/mL Injection.
CEFOTAN (cefotetan injection)
6/9/2006
AstraZeneca Pharmaceuticals LP (AstraZeneca) - Contact Corporate Information Center at 800-236-9933.The remaining inventory of CEFOTAN (cefotetaninjection) has been depleted. AstraZeneca has no further plans to manufacture or distribute CEFOTAN (cefotetan injection). Other cefotetan injection products continue to be available.
Chloral Hydrate Oral Solution5/25/2012Pharmaceutical Associates, Inc
Customer Service: 1-864-277-7282PAI has discontinued manufacturing of Chloral Hydrate Oral Solution 16 fl oz retail package (NDC 00121-0532-16) and 5ml Unit Dose (NDC 00121-0532-05). This is solely a business decision from PAI and is not related to any FDA actions. Cognex (tacrine hydrochloride) Capsules, 10 mg, 20 mg5/24/2012Shionogi, Inc.
800-849-9707Shionogi has made a business decision to discontinue Cognex® (tacrine hydrochloride), 10 and 20 mg capsules.There is no remaining inventory within Shionogi, Inc. distribution network.Cortisporin Ophthalmic Suspension (neomycin and polymyxin B sulfates and hydrocortisone ophthalmic suspension)6/5/2008King Pharmaceuticals
800-776-3637Letter from King Pharmaceuticals
Cortisporin Otic Suspension (neomycin and polymyxin B sulfates and hydrocortisone otic suspension, USP)
6/5/2008
King Pharmaceuticals800-776-3637Letter from King Pharmaceuticals Cyanide Antidote Kit5/22/2012Akorn Pharmaceuticals
1-800-932-5676
Akorn is discontinuing the manufacture of this product and the components for use in this product.Cylert (pemoline) tablets and chewable tablets, all strengths5/25/2005
Abbott Laboratories
Abbott has made the decision to discontinue Cylert tablets and chewable tabletsLetter from Abbott
Cytoxan (cyclophosphamide) 25mg and 50mg tablets
9/24/2007
Bristol-Myers Squibb Company609-897-2412Bristol-Myers Squibb Company has made a decision to discontinue Cytoxan (cyclophosphamide) 25mg and 50mg tablets. Alternate products continue to be available from other companies.
Desyrel (trazodone) Tablets 50mg, 100mg, 150mg and 300mg tablets
9/21/2006
Bristol-Myers Squibb Company609-897-2412
Alternate products continue to be available from other companies.
Dear Healthcare Professional Letter
Digoxin Injection
0.25 mg/mL, 2 mL
5/15/2012
1-609-627-8500 Sandoz discontinued manufacturing in March 2011. Sandox is no longer distributing with no plans for re-introduction.
ELAVIL (amitriptyline hydrochloride) Tablets and Injection.
5/15/2003
AstraZeneca Pharmaceuticals LP (AstraZeneca) – Contact Corporate Information Center at:800-236-9933ELAVIL Injection is no longer available at AstraZeneca. The remaining inventory of ELAVIL Tablets will be depleted by December 31, 2003. AstraZeneca has no further plans to manufacture ELAVIL (amitriptyline hydrochloride) Tablets or Injection.Ephedrine Sulfate Injection 50mg/ml (NDC 00409-3073-31)2/8/2011
Hospira, Inc.
1-877-946-7747Hospira has made a business decision to discontinue manufacturing this product. Akorn and Sandoz continue to have product available.Dear Valued Customer Letter (PDF - 70KB)
Ethmozine (moricizine hydrochloride) 200mg, 250g, and 300mg tablets
9/17/2007
Shire US Inc.725 Chesterbrook Blvd.
Wayne, Pa 19087
1-800-828-2088Dear Healthcare Professional Letter
Exubera (insulin recombinant human, powder for inhalation)
10/19/2007
Pfizer800-398-2372Dear Healthcare Provider Letter
updated
1/14/2011
AstraZeneca Pharmaceuticals LP (AstraZeneca)
Contact the Corporate Communication Center at 1-800-236-9933
There is no remaining inventory within AstraZeneca's distribution network. The final expiration date of any Faslodex* (fulvestrant) Injection that may still be remaining in the market place is December 31, 2010.
AstraZeneca is discontinuing supply of the single dose pack. Inventory depletion is expected the week of Jan 17, 2010. The dual dose pack (NDC 0310-0720-10), two 5.0ml syringes (250mg/5ml) continues to be available.
Florinef (fludrocortisone acetate tablets, USP)
6/8/2007
King Pharmaceuticals, Inc. 501 Fifth Street Bristol, Tennessee 37620 Professional Information Services Department:800-776-3637Dear Healthcare Provider Letter
Flovent Rotadisk (fluticasone propionate inhalation powder)
8/31/2004
GlaxoSmithKline888-825-5249Please see Dear Healthcare Professional letter for additional information.
Fortovase (saquinavir) capsules 200 mg
6/2/2005
RocheFortovase 200 mg capsules will be discontinued by February 15, 2006. Please see attached DHP letter for additional information.
Dear Healthcare Professional Letter
Foscavir (foscarnet sodium) injection
10/31/2008
AstraZeneca Pharmaceuticals LP (AstraZeneca)Contact Corporate Information Center at 1-800-236-9933
Geocillin (carbenicillin indanyl sodium) tablets 382 mg
4/8/2008
PfizerPfizer has discontinued this product. There are no other FDA approved manufacturers currently for carbenicillin tablets.Geref Diagnostic (sermorelin acetate for injection) 0.05mg base/amp
8/5/2008
EMD Serono1-888-398-4567
EMD Serono has made a business decision to discontinue this product.
Dear Healthcare Professional Letter
Baxter Customer Service:
(1-888-229-0001)Heparin Sodium and 0.9% Sodium Chloride Injection product remains available.
Dear Valued Baxter Customer Letter (PDF - 29KB)
Humatin (Paromomycin Sulfate Capsules, USP)
2/7/2008
King Pharmaceuticals Professional Information Services Department800-776-3637
King Pharmaceuticals has made a decision to discontinue Humatin (Paromomycin Sulfate Capsules, USP) Paromomycin continues to be available from another manufacture.
Letter from King Pharmaceuticals
updated
10/26/2010
Eli Lilly and Company
1-800-545-5979
Dear Healthcare Professional Letter (PDF - 201KB)
Patient Information (PDF - 887KB)
Humulin U ULTRALENTE (HUMAN INSULIN [rDNA ORIGIN] EXTENDED ZINC SUSPENSION)
7/6/2005
Eli Lilly and CompanyHumulin L LENTE (HUMAN INSULIN [rDNA ORIGIN] ZINC SUSPENSION)
7/6/2005
Eli Lilly and Company
HIVID (zalcitabine) tablets
7/26/2006
Roche PharmaceuticalsThe sale and distribution of its anti-HIV
medication HIVID (zalcitabine) Tablets will be discontinued by December 31, 2006.
Dear Health Care Professional Letter
Intal Inhaler (cromolyn sodium inhalation aerosol)
8/3/2009
King PharmaceuticalsDear Healthcare Professional LetterIntal Nebulizer Solution (cromolyn sodium inhalation solution, USP)
6/2/2008
King Pharmaceuticals800-776-3637Letter from King Pharmaceuticals
Inversine (mecamylamine hydrochloride) Tablets, 2.5 mg
6/17/2009
Targacept, Inc.336-480-2100Dear Healthcare Professional Letter
Inulin in Sodium Chloride Injection, USP
9/26/2003
Kefzol (cefazolin) all presentations
2/28/2003
Eli Lilly and CompanyLetterKefurox (cefuroxime) all presentations
2/28/2003
Eli Lilly and CompanyLetterKemadrin (procyclidine hydrochloride)
6/6/2008
King Pharmaceuticals800-776-3637Letter from King Pharmaceuticals
Lanoxin Elixir(digoxin)
6/3/2005
GlaxoSmithKlineThis product has been discontinued by GSK.Roxane is producing digoxin elixir.
LEXXEL (enalapril maleate-felodipine ER) Tablets
12/19/2007
AstraZeneca LP (AstraZeneca) - Contact Corporate Information Center at
800-236-9933.
LEXXEL Tablets will be discontinued on July 31, 2008. AstraZeneca has no further plans to manufacture or distribute LEXXEL (enalapril maleate-felodipine ER) Tablets after July 31, 2008.Lorabid(loracarbef, USP) capsules and suspension
10/27/2006
King Pharmaceuticals 888-840-5370Letter from King PharmaceuticalsMandol (cefamandole) all presentations
2/28/2003
Eli Lilly and CompanyLetterMebaral (mephobarbital) 32mg tablets, 50mg tablets and 100mg tablets1/6/2012Lundbeck Inc. Customer service number:
1-888-514-5204
Lundbeck is aware of the difficult situation that some patients may face with regard to the upcoming Mebaral discontinuation. The company thoroughly evaluated all avenues for keeping Mebaral available to patients, but ultimately concluded that no matter what steps we took, patients would be forced to transition to a new therapy. Due to the limited remaining Mebaral supply, we encourage patients to work with their physician to transition to alternative therapies rather than starting a new course of therapy with Mebaral. For more information or with questions, Lundbeck’s medical information team can be reached at 866-402-8520.
Mebendazole Tablets10/26/2011Teva Pharmaceuticals1-800-545-8800Dear Valued Customer Letter (PDF - 43KB)Methergine (methylergonovine maleate)
Injection and Tablets
4/12/2012
Novartis Pharmaceuticals Corporation
1-888-NOW-NOVA
Novartis Pharmaceuticals Corporation has made a decision to discontinue Methergine (methylergonovine maleate) tablets and injection.Mitozytrex (Mitomycin for Injection)
9/12/2008
SuperGen
(925) 560-0100
Other Mitomycin approved products continue to be available.
This product was never commercialized.
Mivacron (mivacurium chloride) injection
6/23/2006
Abbott LaboratoriesAlternative products that can be used in place of Mivacron continue to be available. Please call Abbott at 1-800-633-9110 for additional information.
Moban (molindone hydrochloride)
5 mg, 10 mg, 25 mg, and 50 mg Tablets
1/13/2010
Endo Pharmaceuticals Inc.1-800-462-ENDO (1-800-462-3636)Moban tablets have been discontinued and supplies are anticipated to be depleted by June 30, 2010.
Naltrexone Oral Tablets
50 mg, 100 count
5/15/2012
1-609-627-8500 Product is discontinued. Sandox is no longer distributing with no plans for re-introduction.
Nandrolone Decanoate Injection
6/24/2009
Watson Pharmaceuticals(800) 272-5525Watson Pharmaceuticals has discontinued this product because of the unavailability of the active pharmaceutical ingredient.
Neutrexin (trimetrexate glucuronate) Injection
6/14/2007
MedImmune, Inc.Dear Healthcare Professional LetterNimotop (nimodipine) capsules
10/31/2008
Bayer HealthCare Pharmaceuticals888-842-2937
Generic nimodipine remains available.
Please see Dear Healthcare Professional Letter for additional information.
Nolvadex (tamoxifen citrate)
4/10/2006
800-236-9933Letter
Novolin InnoLet disposable pens and Novolin PenFill 3 mL cartridges for Novolin R, N and 70/30
8/13/2009
Novo Nordisk1-800-727-6500Dear Healthcare Provider Letter
Dear Patient Letter
Novolin L, Lente, human insulin zinc suspension [rDNA origin]
7/15/2003
Novo Nordisk Pharmaceuticals, Inc.
Contact:
800-727-6500 Customer Service
Letter
NPH Iletin II (ISOPHANE INSULIN SUSPENSION, USP, PURIFIED PORK)
7/6/2005
Eli Lilly and CompanyOndansetron Injection, 2 mg/mL2 mL vials, package of 5 (NDC 60505-0744-01)20 mL multiple dose vial (NDC 60505-0744-06)4/10/2012 Apotex Corporation Customer Service:
1-(877)-4-ApotexApotex has discontinued the manufacturing of Ondansetron Injection. Ondansetron Injection 32 mg/50 mL premixed bags5/18/2012West-Ward Pharmaceuticals
Customer Service:
1-888-229-0001West-Ward no longer distributes Ondansetron premixed bags.
Opana ER strengths 7.5 mg and 15 mg3/1/2011
Endo Pharmaceuticals Inc.
1-800-462-ENDO
(1-800-462-3636)Endo Pharmaceuticals Inc. has have made a business decision to discontinue the 7.5 mg and 15 mg strengths. The 7.5 mg and 15 mg strengths will continue to be available through pharmacies until all inventory is depleted. All other strengths remain available.Dear Valued Customer Letter (PDF - 55KB)
Original Prefilled Pen that Contains Humalog, Humalog Mix 75/25, and Humalog Mix 50/50updated10/26/2010Eli Lilly and CompanyBy the end of October, it is anticipated that the original Prefilled Pen containing Humalog Mix50/50 will no longer be available for ordering or shipping by wholesalers, distributors and pharmacy buyers. Supplies will be depleted by that time, and additional product will not be manufactured. At this time, the original Prefilled Pen containing Humalog or Humalog Mix75/25 continues to be available and orders will be shipped until supplies are exhausted.
ORLAAM (Levomethadyl hydrochloride acetate) Oral Solution, 10 mg/mL
9/2/2003
Roxane LaboratoriesLetterPancrease (pancrelipase) capsules
5/17/2006
McNeil Consumer and Specialty Pharmaceuticals888-440-7903
Other pancrelipase products continue to be available
Dear Health Care Provider Letter
Pentothal (thiopental) Injection1/25/2011 Hospira Pharmaceuticals
1-877-946-7747Hospira has made the decision to discontinue this product.Perchloracap (potassium perchlorate) 200 mg capsules6/2/2005Tyco HealthcarePerchloracap capsules have been discontinued and supplies are anticipated to be depleted by the end of 2005. Phenobarbital Oral Solution 4/5/2012Pharmaceutical Associates, Inc
Customer Service: 1-864-277-7282PAI has discontinued manufacturing of Phenobarbital Oral Solution (20mg/5mL) 5 mL unit dose package (NDC-00121-0531-05).Pontocaine HCL Injection (all products)12/9/2010
Hospira, Inc.
1-877-946-7747
Hospira has made a business decision to discontinue these products. http://hospiraadvancewithus.com/
Potassium Citrate and Citric Acid Oral Solution
4/5/2012
Pharmaceutical Associates, Inc
Customer Service:
1-864-277-7282
PAI has discontinued manufacturing of Potassium Citrate and Citric Acid Oral Solution: Potassium Citrate Monohydrate 1100 mg/5 ml; Citric Acid Monohydrate 334 mg/5 ml (NDC 00121-0676-16).Procanbid (Procanamide Hydrochloride Extended-Release Tablets)
11/9/2007
King Pharmaceuticals 800-776-3637Dear Prescriber Letter5/2/2007
Abbott200 Abbott Park Road Abbott Park, IL 60064-6157
Customer Service: 800-633-9110Dear Health Care Provider Letter
PulmicortTurbuhaler 200mcg (budesonide inhalation powder)
5/16/2007
AztraZeneca1800 Concord Pike PO Box 8355 Wilmington DE 19803-8355
Corporate Information:
800-842-9920
NDA 20-441, PULMICORT TURBUHALER 200 mcg (budesonide inhalation powder) will no longer be available at AstraZeneca.
The introduction of PULMICORT FLEXHALER (budesonide inhalation powder, 90 & 180 mcg), NDA 21-949, will be accompanied by the phasing out of PULMICORT TURBUHALER so as to minimize confusion in the marketplace.
AstraZeneca has no further plans to manufacture NDA 20-441, PULMICORT TURBUHALER 200 mcg (budesonide inhalation powder).
Refludan (lepirudin (rDNA)) for Injection5/17/2012Baxter Healthcare CorporationCustomer Service:
1-888-229-0001Baxter Healthcare Corporation has made a decision to discontinue Refludan (lepirudin (rDNA)) for Injection. No further product will be distributed from Bayer after May 31, 2012.Regular Iletin II (INSULIN INJECTION, USP, PURIFIED PORK)7/6/2005 Eli Lilly and Company Revex (Nalmefene HCl Injection) 1mg/mL, 2 mL ampule and 0.1mg/mL, 1mL ampule7/9/2008Baxter Healthcare Corporation
888-229-0001
Baxter has discontinued Revex production.Roferon-A (Interferon alfa-2a, Recombinant)11/29/2007Hoffmann -La Roche Inc.
800-526-6367Dear Healthcare Professional Letter
SecreFlo (porcine secretin for injection, 16 mcg/vial)
10/1/2008
ChiRhoClin, Inc., 1-877-272-4888Please see Dear Healthcare Professional Letter for additional information.
Serevent Inhalation Aerosol
6/10/2003
GlaxoSmithKline800-340-3236
GSK anticipates that SEREVENT Inhalation Aerosol will no longer be available starting in June 2003.
Dear Health Care Professional Letter from GlaxoSmithKline
Sporanox (itraconazole) Injection
10/11/2007
Ortho BiotechPlease see Dear Health Care Professional letter for additional information.Stelazine (trifluoperazine) oral concentrate 10mg/ml
Stelazine (trifluoperazine) tablets (1mg, 2mg, 5mg, 10mg)
Stelazine (trifluoperazine) Injection 2mg/ml
12/18/2003
GlaxoSmithKline888-825-5249Stelazine was discontinued and withdrawn from the market. The final lots were distributed by GSK August 2003 and the final expiry date of all products in the marketplace is no later than January 31, 2004.
Suprax (cefixime)
updated 2/25/2004
Lederle/Wyeth PharmaceuticalsDiscontinued July 2002. Stock will be distributed until exhausted or until March 2003, whichever comes first. For additional information, please call customer service (800) 666-7248
Lupin Pharmaceuticals recently received approval for cefixime 400 mg tablets and cefixime 100 mg/5 ml suspension. For further information, please contact Lupin Pharmaceuticals at 410-576-2000 (2/25/2004)
Tenormin (atenolol) 0.5mg/ml Injection
2/28/2008
AstraZeneca Pharmaceuticals LP (AstraZeneca) – Contact Corporate Information Center:800-236-9933AstraZeneca has made a business decision to discontinue Tenormin (atenolol) 0.5 mg/ml injection.
Teslac (testolactone tablets, USP) 50mg tablets
2/26/2008
Bristol-Myers Squibb609-897-2412
Bristol-Myers Squibb Company has made a decision to discontinue Teslac (testolactone tablets, USP) 50mg tablets.
Letter from Bristol-Myers Squibb
Tequin (gatifloxacin) Tablets and Injection
5/12/2006
Bristol-Meyers SquibbSee attached letter
Tilade Inhaler (nedocromil sodium inhalation aerosol)
5/2/2008
King Pharmaceuticals800-776-3637Dear Healthcare Professional Letter (4/30/2008) Tricitrates Oral Solution
4/5/2012 Pharmaceutical Associates, Inc
Customer Service:
1-864-277-7282 PAI has discontinued manufacturing of Tricitrates Oral Solution: Potassium Citrate Monohydrate 550 mg/5 mL; Sodium Citrate Dihydrate 500 mg/5 mL; Citric Acid Monohydrate 334 mg /5 mL (NDC 00121-0779-16). Tricitrates SF Oral Solution 4/5/2012Pharmaceutical Associates, Inc
Customer Service: 1-864-277-7282PAI has discontinued manufacturing of Tricitrates SF Oral Solution: Potassium Citrate Monohydrate 550 mg/5 mL; Sodium Citrate Dihydrate 500 mg/5 mL; Citric Acid Monohydrate 334 mg /5 mL (NDC 00121-0677-16).Valstar (valrubicin) Solution for Intravesical Instillation1/30/2004Formerly distributed by Celltech
Celltech Customer Service
888-963-3382
No further availability planned at this time.Velosulin BR Human, Buffered Regular Human Insulin Injection [rDNA origin]11/3/2003
Novo Nordisk Pharmaceuticals, Inc.
Contact:
800-727-6500
Customer Service Dear Healthcare Professional Letter
Vesanoid (tretinoin) Soft Gelatin Capsule 10 mg
12/17/2009
Hoffmann-La Roche IncPlease see the Dear Customer Letter titled: Vesanoid 10mg (tretinoin) Product Deletion at: Vesanoid
Teva is increasing supply of their tretinoin 10mg capsules to meet market demand (NDC 00555-0808-02).
Videx (didanosine) chewable/dispersable buffered tablets
9/19/2006
BMSDear Healthcare Professional Letter1.5% Xylocaine -MPF with Dextrose 7.5% Injection (lidocaine HCl and dextrose anhydrous Injection ampules)
8/29/2005
AstraZeneca
800-842-9920
1.5% Xylocaine® -MPF with Dextrose 7.5% Injection is no longer available at AstraZeneca. The remaining inventory of 1.5% Xylocaine® -MPF with Dextrose 7.5% Injection Ampules will be depleted by August 31, 2005. AstraZeneca has no further plans to manufacture 1.5% Xylocaine® -MPF with Dextrose 7.5% Injection Ampules
Zenapax (daclizumab) sterile Concentrate for Injection
12/18/2009
Hoffman-La RochePlease see Dear Healthcare Professional Letter for additional informationZovirax (acyclovir sodium) for injection 1000mg/20ml vial
1/6/2004
GlaxoSmithKlineCustomer Service
800-877-1158
Letter from GSK
Zyflo (zileuton) tablets
2/20/2008
Critical Therapeutics, Inc.Zyflo CR continues to be available.
Read more http://www.fda.gov/Drugs/DrugSafety/DrugShortages/ucm050794.htm#cyanide